Clinical Study of Sixty-Three Cases of Oriental Sore

own experiences with antimony (trivalent and pentavalent compounds) and emetine conform to the results obtained by Captain Goodall and, of course, are quite unsatisfactory. Berberine was mainly used in the British Military Hospital and their reports were just as unsatisfactory. From the start the results of treatment with these drugs were carefully watched and compared with each other" and with the procedure of scraping the sore and carbolizing. Excising the ulcer was tried in two selected cases but discarded at once owing to inability to maintain asepsis. However, the results of scraping and carbolizing were so dramatically successful and vastly superior to the medical treatment that it became routine treatment. Captain de L. Carey, i.m.s.. then suggested intravenous injection of 10 c.cm. of 10 per cent calcium chloride on alternate days for selected cases that did not seem suitable for the surgical procedure. I have forgotten the authority Captain Carey quoted. Such cases were sores on the evelid of great multiplicitv. This treatment dried up the sores much more quickly than the antimonv salts and was not toxic. However, it scleroses the veins and therefore has a limited application. The scraping was so much the best procedure that I will brieflv describe the points in it. It was done under nitrous oxide eras. Occasionally, there were two or more operations taking an area each. e.a., two limbs or the face. Scraping is very firm and vigorous indeed with a Volkmann's spoon or curette. One invariably reached a dense fibrous base through which it was almost impossible to scrape. The material scraped away was cheesy and friable. The edge of the wound including apnarentlv healthy skin also came away. The picture is so characteristic that if it is not met with, one can assume a wrong diagnosis. The oozing was then stopped for a moment bv gauze pressure and the whole raw area painted with pure liquid carbolic acid. Finally, the wound is covered directly with elastoplast?or adhesive strapping in its absence? without intervening gauze or other dressing, and the whole bandaged up. The strapping or elastoplast was not removed for 14 days. The discharge from beneath it became gradually less, and at the end of 14 days,